Search and rescue teams and sniffer dogs from the Italian Red Cross are on the ground following a 6.2 magnitude earthquake in the early hours of the this morning.
The towns of Amatrice, Accumoli and Arquata del Tronto village in central Italy are the worst affected areas.
The Red Cross has also sent 20 ambulances to the affected areas, while local volunteers are on the ground providing support for survivors.
Italian Red Cross spokesman Tommaso Della Longa said: “The pictures that we have received from our colleagues in Amatrice are telling us a terrible story of a town almost completely destroyed.
"Our priority right now is finding survivors.”
Mobile kitchens are also being set up for people who have been forced to leave their homes. A 24-hour emergency control centre has been activated in Rome, while the Red Cross is also working from a mobile operations centre in the quake zone.